Resources & Blog
Technical Resources
Application notes, technical guides, CoA documentation help, and RUO compliance resources for research professionals.
All resources are provided for qualified research professionals only. Direct Research Peptides products are For Research Use Only (RUO). Not for human or animal consumption.
Technical Articles
Understanding Peptide Purity Grades
What ≥85%, ≥95%, and ≥98% HPLC purity means for your research and how to choose the right grade.
Epitope Tags: Selection & Application Guide
HA, FLAG, His, Myc, V5 — a comprehensive guide to choosing the right tag for your expression system.
How to Read a Peptide Certificate of Analysis
Walk through every field on a CoA including HPLC peak areas, MS data, and calculated vs. theoretical MW.
Custom Synthesis: Common Modification Requests
Phosphorylation, biotinylation, fluorescent labels, PEGylation — what's possible and how to specify them.
Peptide Storage & Reconstitution Best Practices
Lyophilized peptide storage conditions, solvent selection, and freeze-thaw cycle recommendations.
RUO Compliance: What Researchers Need to Know
Research Use Only regulations, institutional requirements, and Direct Research Peptides' compliance documentation.
Certificate of Analysis Library
CoAs are available from our testing / CoA library for applicable catalog products.
Open the CoA Library
Browse and download Certificates of Analysis by product, catalog number, or lot.
Peptide Design & Modeling Software
Computational tools for structure prediction, binding design, and peptide property modeling — for research use.
AI-powered peptide and small molecule interaction modeling. Predict binding poses, affinity estimates, and solubility profiles for peptide research candidates.
DeepMind's landmark protein structure prediction tool. Predict 3D structures for target proteins and tagged fusion constructs to guide peptide epitope selection.
De novo protein binder design pipeline. Generate high-confidence peptide binders computationally using RFdiffusion-based backbone generation and sequence design.
Generative biology platform for structure-based peptide and small molecule design. Supports non-canonical amino acids and modified residue contexts.
Structure prediction server for peptides including modified residues, cyclic peptides, and peptides with non-natural amino acids.
High-resolution peptide-protein docking refinement using RosettaCommons. Model peptide binding modes in receptor groove geometries with full-atom refinement.
Recommended Books
Essential reading for researchers working with synthetic peptides and AI-driven research design.
Applied Artificial Intelligence in Drug Discovery
2024
Covers AI applications in target identification, peptide design, hit-to-lead optimization, and computational screening for research laboratories.
Peptide Synthesis: Methods and Protocols
2023
Springer Protocols volume covering solid-phase synthesis methods, modification chemistry, HPLC purification, and analytical characterization of synthetic peptides.
Artificial Intelligence in Drug Discovery
2021
RSC series on machine learning and deep learning methods for early-stage research, peptide library design, and synthesis planning.
Fmoc Solid Phase Peptide Synthesis
2000 (Oxford)
The definitive reference for Fmoc SPPS including coupling chemistry, side-chain protection strategies, cleavage conditions, and modification protocols.